기업부설연구소 - 엘림랜드

엘림랜드(주)는 기업부설연구소를 통해 안전하고 건강한 제품을 만들기 위해 최선을 다합니다.

1. 연구소장 소개

연구소장

이광호

Kyoto University, 일본 의학박사

경력

1983 - 1985 교육조교(건국대학교 축산대학)
1992 - 1995 조교수 건국대학교 자연과학대학 분자생물학과
1996 - 2000 부교수 동일학과(1999년부터 생명과학부 생명공학전공으로 명칭변경)
2001 - 교수
1985 - 1986 일본 문부성 초청 연구생(일본 교토대학 의학부 의화학 교실)
1990 - 1992 객원연구원(Visiting Fellow)미국 국립보건연구소 (Laboratory of Immunology. NIAID. NIH)
U. S. A. Advisor; Dr. Michael J. Lenardo 1999-2000 초빙 연구원(Inviting Researcher)
Department of Experimental Immunology.
Institute of Development, Aging and Cancer (일본 동북대학 가령의학 연구소)

주요논문

A novel family of variable region genes of human immunoglobulin heavy chain (지도교수; Dr. Tasuku Honjo)
2001년 4월한국과학기술단체 총 연합회 “과학기술 우수논문상”수상

주요저서

Do-Wan Shim, Hee Jae Shin, Ji-Won Han, Young-Eun Ji, Cheol-Hun Jang, Sushruta Koppula, Tae-Bong Kang and Kwang-Ho Lee. (2015) A novel synthetic derivative of melatonin, 5-hydroxy-2’-isobutyl-streptochlorin (HIS), inhibits inflammatory responses via regulation of TRIF-dependent signaling and inflammasome activation.
Toxicology and Applied Pharmacology. 284: 227-235
Ji-Won Han, Do-Wan Shim, Eun-Jeong Shim, Myong-Ki Kim, Yong-Kook Shin, Su-Bin Kwak, Sushruta Koppula, Tack-Joong Kim, Tae-Bong Kang, Kwang-Ho Lee. (2015) Syneilesis palmata (Thunb.) Maxim. extract attenuates inflammatory responses via the regulation of TRIF-dependent signaling and inflammasome activation.
Journal of Ethnopharmacology. 166: 1-4
Do-Wan Shim, Hee Jae Shin, Ji-Won Han, Woo-Young Shin, Xiao Sun, Eun-Jeong Shim, Tack-Joong Kim, Tae-Bong Kang and Kwang-Ho Lee. (2015) Anti-Inflammatory Effect of Streptochlorin via TRIF-Dependent Signaling Pathways in Cellular and Mouse Models. International Journal of Molecular Sciences 16: 6902-6910
Do-Wan Shim, Kang-Hyuck Heo, Young-Kyu Kim, Eun-Jeong Sim, Tae-Bong Kang, Jae-Wan Choi, Dae-Won Sim, Sun-Hee Cheong, Seung-Hong Lee, Jeong-Kyu Bang, Hyung-Sik Won and Kwang-Ho Lee. (2015) Anti-inflammatory Action of an Antimicrobial Model Peptide That Suppresses the TRIF-dependent Signaling Pathway via Inhibition of Toll-Like Receptor 4 Endocytosis in Lipopolysaccharide-Stimulated Macrophages. PLOS ONE 10(5): 1-13
Ji-Won Han, Do-Wan Shim, Woo-Young Shin, Kang-Hyuk Heo, Su-Bin Kwak, Eun-Jeong Sim, Jae-Hyun Jeong, Tae-Bong Kang, Kwang-Ho Lee. (2015) Anti-inflammatory effect of emodin via attenuation of NLRP3 inflammasome activation. International Journal of Molecular Sciences. 16: 8102-8109 외 다수

연구분야

종양 면역의 분자생물학적 연구 및 치료제 개발
엘러지의 분자생물학적 연구와 치료제 개발
Lee,K.H., Matsuda,F., Kinash,T., Kodaira,M and Honjo,T.(1987). A novel family of variable region genes of human immunoglobulin heavy chain. J. Mol. Biol. 195;761-768.
Matsuda,F., Lee,K.H., Nakai,S., Sato,T., Kodaira,M.,Zong,S.Q., Ohno,H.,Hukuhara,S and Honjo,T.(1988). Dispersed localization of D segments in the human immunoglobulin heavy-chain locus. EMBO J. 7 (4);1047-1051.
Zong,S.Q., Nakai,S., Matsuda,F., Lee,K.H and Honjo,T.(1988). Human immunoglobulin D segments:Isolation of a new D segment and polymorphic deletion of the D1 segments. Immuol. Lett. 17; 329-333.
Sato,T., Matsuda,F., Lee,K.H., Shin,E.K and Honjo,T.(1988).Physical linkage of variable region segment and the joining region segment of the human immunoglobulin heavy chain locus. Biochem. Biophys. Res. Commun. 154; 265-271.
Nosaka,T., Kita,K., Miwa,H., Kawakami,K., Ikeda,T., Ohno,T., Matsuoka,N., Arita,Y., Doi,S., Nishikori,M.,Matsuda,F., Lee,K.H., Shirakawa,S.Honjo,T and Hatanaka,M.( 1989).Cross-lineage gene rearrangements in human leukemic B-precursor cells occur frequently with V-DJ rearrangements of IgH genes. Blood.74(1);361-368.
Kinashi,T., Tashiro,K., Lee,K.H., Inaba,K., Toyama,K., Palacios,R and Honjo,T.,(1990). Growth factors involved in lymphocyte differentiation. Phil. Trans.R. Soc. Lond. 327;117-125.
Kinash,T., Tashiro,K., Lee,K.H., Inaba,K., Toyama,K., Palacios,R and Honjo,T. (1991). Differentiation of an interleukin-3-dependent precursor cell into myeloid cells as well as B lymphocytes. Int. Conf. Mol. Asp. 외 다수